One of the best known aromatic acetates is acetylsalicylic acid, or aspirin, which is prepared by the esterification of the phenolic hydroxyl group of salicylic acid. Aspirin possesses a number of properties that make it the most often recommended drug. It is an analgesic, effective in pain relief.
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Salicylic acid, a white, crystalline solid that is used chiefly in the preparation of aspirin and other pharmaceutical products. The free acid occurs naturally in small amounts in many plants, particularly the various species of Spiraea. The methyl ester also occurs widely in nature; it is the
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SYNTHESIS OF ASPIRIN (acetylsalicylic acid) Place 2.0 g (0.015 mole) of salicylic acid in a 125-mL Erlenmeyer flask. Add 5 mL (0.05 mole) of acetic anhydride, followed by 5 drops of conc. H 2 SO 4 (use a dropper, H 2 SO 4 is highly corrosive) and swirl the flask gently until the salicylic acid dissolves.
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SummaryAspirin (acetylsalicylic acid) is metabolically converted to salicyclic acid by the action of carboxylesterases. Protein binding displacement appears to be the basis of salicylic acid interactions with diclofenac, flurbiprofen, ibuprofen, isoxicam, ketoprofen, naproxen, phenytoin and...
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Nov 06, 2012 · Aspirin, C9H8O4 , is produced through the following reaction of salicylic acid, C7H6O3, and acetic anhydride, C4H6O3: C7H6O3(s) + C4H6O3(l) ---> C9H8O4(s) + HC2H3O2(l) A. What mass of aspirin (kg) could be produced from 75.0 mol . You can view more similar questions or ask a new question.
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OH OH C OH O O C CH. 3. O OH C O Phenol Salicylic acid (2-Hydroxybenzoic acid) Aspirin (2-ethanoyloxybenzenecarboxylic acid) The OH group attached to the benzene ring produces a purple colour with Fe3+(aq) ions. The OH group in aspirin is part of the carboxylic acid group and does not react in the same way.